semax
COGNITIVE · ACTH FRAGMENT · 7 AA
also: ACTH(4-7)-PGP · MEHFPGP · Semax 0.1%
Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment, extended with a Pro-Gly-Pro tail that slows enzymatic breakdown, and it is registered and marketed in Russia for stroke and cognitive indications. Rodent work fairly consistently reports upregulation of BDNF and NGF expression in hippocampus and cortex, though the human data supporting clinical use remain limited and largely unverifiable outside Russia.
// our evidence grade — unedited
Registered as a medicine in Russia with a published stroke meta-analysis behind it, but essentially the entire human evidence base sits in Russian-language journals that no Western group has independently replicated.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Met-Glu-His-Phe-Pro-Gly-Pro (ACTH(4-7) analogue with C-terminal Pro-Gly-Pro) |
| cas | 80714-61-0 |
| formula | C37H51N9O10S |
| molar mass | 813.9 g/mol |
| purity | ≥ 99% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised powder stable at -20°C protected from light and moisture; after reconstitution store at 2-8°C and use within approximately 2-4 weeks, avoiding repeated freeze-thaw cycles. |
| solubility | Readily soluble in sterile or bacteriostatic water; also soluble in aqueous buffer at neutral pH. |
| sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
// select size
crypto payment · research use only · not for human consumption
// others in Cognitive