tb-500 fragment
Tβ4 CORE MOTIF · 7 AA · ACTIN-BINDING · NO HUMAN TRIALS
also: TB-500 · Ac-LKKTETQ · Tβ4 17-23
TB-500, as characterised in the analytical chemistry literature, is the N-terminally acetylated 17-23 fragment of thymosin beta-4 - the seven-residue LKKTETQ actin-binding motif rather than the intact 43-residue protein. Rodent studies report improved dermal wound repair and angiogenesis attributable to this motif, but no published human interventional trial has evaluated the fragment.
// our evidence grade — unedited
The heptapeptide has a genuine, independently replicated preclinical record in rodent wound-repair models and a defined molecular target in monomeric actin, but no human interventional trial has evaluated it and it is routinely conflated with the full 43-residue thymosin beta-4 protein.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Thymosin beta-4 actin-binding fragment (Tβ4 17-23, LKKTETQ) |
| formula | C36H66N10O13 |
| molar mass | 847 g/mol |
| purity | ≥ 99% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Supplied as a lyophilised powder; research peptide is generally stored desiccated at -20 °C and protected from light. |
| solubility | Freely soluble in water - a short, highly polar peptide with two lysines, no hydrophobic core and no cysteines. |
| sequence | LKKTETQ |
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crypto payment · research use only · not for human consumption
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