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peg-mgf

PEG CONJUGATE OF MGF · BORROWED EVIDENCE · NO STUDIES OF ITS OWN

also: PEG-MGF · PEG MGF · pegylated MGF

PEG-MGF is a polyethylene-glycol conjugate of the 24-residue C-terminal E-domain peptide of IGF-1Ec, the mechanical-load-induced splice variant of IGF-1. No study of the pegylated construct has been published in any species: the single PubMed-indexed source that mentions it is a 2026 review confirming the absence of human clinical data and noting that the effects observed with native IGF-1Ec or unmodified E-domain peptides cannot be assumed to apply to a PEG conjugate. This index grades unmodified MGF at D on the strength of its cell and rodent work; PEG-MGF has no separate evidence base at all.

≥ 98% HPLClyophilised powderbatch COA
F

// our evidence grade — unedited

An exact-phrase PubMed search for 'PEG-MGF' returns exactly one indexed publication — a 2026 endocrinology review which states there are 'no peer-reviewed clinical studies in humans' — and zero records exist for 'pegylated mechano growth factor'; ClinicalTrials.gov returns zero registered studies. Every mechanistic claim made for the product belongs to unmodified MGF or to endogenous IGF-1Ec, and the pegylation is precisely the change that blocks transfer of that evidence.

We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.

read the full evidence →

// specification

full namePEGylated mechano growth factor — a polyethylene-glycol conjugate of the IGF-1Ec C-terminal E-domain peptide
purity≥ 98% HPLC
formlyophilised powder, sealed vial
storageLyophilised powder is stored desiccated at -20 °C and protected from light. Once reconstituted, laboratory practice is refrigeration at 2-8 °C for short-term use, or aliquoting and freezing to avoid repeated freeze-thaw cycles. Handling information only; this material has no approved human use.
solubilityShort hydrophilic peptide, readily soluble in sterile or bacteriostatic water and in dilute aqueous buffer. Lot-specific solubility is stated on the certificate of analysis.

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crypto payment · research use only · not for human consumption

peg-mgf is supplied as a laboratory research reagent. It is not a medicine and is not for human or animal consumption. We publish no dosing, no administration route and no protocol, and will not provide them on request.

// others in Growth Hormone