pancragen
TETRAPEPTIDE AMIDE · KHAVINSON PANCREAS BIOREGULATOR · KEDW · ONE UNCONTROLLED HUMAN SERIES
also: KEDW · Lys-Glu-Asp-Trp-NH2 · lysyl-glutamyl-aspartyl-tryptophanamide
Pancragen is the pancreas-directed member of the Khavinson short-peptide series, published as the tetrapeptide amide Lys-Glu-Asp-Trp-NH2. Its evidence consists of in vitro work on pancreatic cell differentiation markers, a streptozotocin diabetes model, glucose-tolerance experiments in old rhesus monkeys, and one small uncontrolled human observation in elderly type 2 diabetes. Every one of those reports is co-authored by Khavinson and appears in Bulletin of Experimental Biology and Medicine or Advances in Gerontology.
// our evidence grade — unedited
The entire human record is a single non-randomised, non-blinded, placebo-free comparison in 33 elderly type 2 diabetes patients from the originating collaboration, with zero registered trials on ClinicalTrials.gov and no replication by any laboratory not co-authored by Khavinson in nearly two decades.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Pancragen (lysyl-glutamyl-aspartyl-tryptophanamide; H-Lys-Glu-Asp-Trp-NH2) |
| formula | C26H37N7O8 |
| molar mass | 575.6 g/mol |
| purity | ≥ 98% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised powder is stored desiccated at -20 °C and protected from light. Once reconstituted, laboratory practice is refrigeration at 2-8 °C for short-term use, or aliquoting and freezing to avoid repeated freeze-thaw cycles. Handling information only; this material has no approved human use. |
| solubility | Short hydrophilic peptide, readily soluble in sterile or bacteriostatic water and in dilute aqueous buffer. Lot-specific solubility is stated on the certificate of analysis. |
| sequence | Lys-Glu-Asp-Trp (KEDW); published as the C-terminal amide H-Lys-Glu-Asp-Trp-NH2 |
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crypto payment · research use only · not for human consumption
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