n-acetyl epitalon
LONGEVITY · ACETYLATED AEDG ANALOGUE · NO INDEPENDENT EVIDENCE
also: N-acetyl epithalon · NA-epitalon · Ac-AEDG
N-Acetyl epitalon is the tetrapeptide epitalon (Ala-Glu-Asp-Gly) with an acetyl group on the N-terminal alanine, sold by research-chemical vendors as a supposedly more stable or more bioavailable version of epitalon. PubChem records the free-acid form as a distinct compound, but no published study of any kind has tested it. The longevity, telomerase and pineal claims attached to it belong entirely to the unmodified peptide.
// our evidence grade — unedited
PubMed returns zero records for N-acetyl epitalon under any spelling and ClinicalTrials.gov returns zero registered studies for epitalon in any form, so there is not one published experiment - human, animal or in vitro - on the acetylated molecule itself. Every claim made for it is transposed from unmodified epitalon, whose own record is a single St Petersburg group publishing largely in Russian journals and which this index already grades D.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | N-Acetyl epitalon (N-acetyl-Ala-Glu-Asp-Gly), the N-terminally acetylated analogue of the pineal tetrapeptide epitalon |
| formula | C16H24N4O10 |
| molar mass | 432.38 g/mol |
| purity | ≥ 98% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised powder is stored desiccated at -20 °C and protected from light. Once reconstituted, laboratory practice is refrigeration at 2-8 °C for short-term use, or aliquoting and freezing to avoid repeated freeze-thaw cycles. Handling information only; this material has no approved human use. |
| solubility | Short hydrophilic peptide, readily soluble in sterile or bacteriostatic water and in dilute aqueous buffer. Lot-specific solubility is stated on the certificate of analysis. |
| sequence | Ac-Ala-Glu-Asp-Gly |
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crypto payment · research use only · not for human consumption
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