mgf
IGF-1 SPLICE VARIANT · 24 AA E-DOMAIN · NO HUMAN TRIALS
also: MGF · IGF-1Ec · IGF-1 Ec E-peptide
MGF is the 24-amino-acid C-terminal E-domain peptide of IGF-1Ec, a splice variant of IGF-1 that is upregulated in skeletal muscle after mechanical loading and damage. Preclinical work supports a role in activating muscle satellite cells and in rodent cardiac and neuromuscular injury models, but no controlled human trial of the synthetic peptide has been published.
// our evidence grade — unedited
A genuine, well-characterised IGF-1 splice product with reproducible effects on human muscle progenitor cells and rodent injury models, but with no human interventional trial and an authoritative review co-authored by its own discoverers stating that its efficacy in man is not proven.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Mechano growth factor (IGF-1Ec C-terminal E-domain peptide, MGF-24aa-E) |
| formula | C121H194N40O40 |
| molar mass | 2849.1 g/mol |
| purity | ≥ 99% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Supplied as a lyophilised powder; research peptide is generally stored desiccated at -20 °C and protected from light. |
| solubility | Soluble in water; the sequence is strongly basic with two arginines and three lysines, and the review literature notes that synthetic E-peptides benefit from chemical stabilisation. |
| sequence | YQPPSTNKNTKSQRRKGSTFEEHK |
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crypto payment · research use only · not for human consumption
// others in Growth Hormone