dsip
ORPHAN NONAPEPTIDE SLEEP FACTOR
also: DSIP · delta sleep peptide · emideltide
DSIP is a nonapeptide isolated from the cerebral venous blood of sleeping rabbits and named for an electroencephalographic delta-wave effect that later work struggled to reproduce. Nearly five decades on, no specific receptor or precursor gene has been identified and the peptide has no approved therapeutic use.
// our evidence grade — unedited
Isolated in the mid-1970s and sequenced in 1977, DSIP still has no approved indication anywhere, no identified receptor, precursor protein or gene, and the small human sleep trials that exist were weak or explicitly negative.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Delta sleep-inducing peptide |
| cas | 62568-57-4 |
| formula | C35H48N10O15 |
| molar mass | 848.82 g/mol |
| purity | ≥ 99% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised peptide is typically stored desiccated at -20 C and protected from light; reconstituted aqueous solutions are unstable given the peptide's rapid enzymatic degradation. Handling information only. |
| solubility | Water-soluble; the nonapeptide is amphiphilic with acidic Asp and Glu residues and dissolves readily in aqueous buffers. |
| sequence | Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu (WAGGDASGE) |
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crypto payment · research use only · not for human consumption
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