dermorphin
ULTRA-POTENT MU-OPIOID HEPTAPEPTIDE
also: frog juice · sapo · Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2
Dermorphin is a naturally occurring opioid heptapeptide from the skin of South American Phyllomedusa frogs whose D-alanine residue confers protease resistance and extreme mu-opioid receptor selectivity. It has no approved human medical use and is known publicly almost entirely through horse-racing doping enforcement, where it is classified among the most severe prohibited agents.
// our evidence grade — unedited
A mu-opioid agonist reported at roughly 30 to 40 times the potency of morphine by weight, with no approved human medical use anywhere, no human safety database, and a public record consisting chiefly of racehorse doping enforcement; the overdose and respiratory-depression risk is real and unmitigated.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Dermorphin |
| cas | 77614-16-5 |
| formula | C40H50N8O10 |
| molar mass | 802.89 g/mol |
| purity | ≥ 98% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised peptide is typically stored desiccated at -20 C and protected from light. Handling information only; this compound has no approved human use. |
| solubility | Soluble in water and aqueous buffers; the amidated C-terminus and Tyr/Ser residues give it good aqueous solubility. |
| sequence | H-Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2 |
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crypto payment · research use only · not for human consumption
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