Cortagen
AEDP TETRAPEPTIDE · KHAVINSON BIOREGULATOR · 4 AA · PRECLINICAL ONLY
also: AEDP · Ala-Glu-Asp-Pro · cortical peptide bioregulator
Cortagen is a synthetic tetrapeptide (AEDP) from Khavinson's St Petersburg group, marketed as a cortical or brain 'bioregulator'. Its literature is the broadest of the five here: rat sciatic-nerve regeneration, a mouse cardiac microarray study, free-radical and chromatin-decondensation assays, and Russian-language pharmacology work on experimental brain ischaemia. All of it is preclinical, and no human study or registered trial exists.
// our evidence grade — unedited
Cortagen has the largest literature in this family — around fifteen indexed papers including rat nerve-regeneration work and one non-Khavinson in vitro group in Tbilisi — but there is still no registered trial, no published human study, and the originating group's own 2014 review of clinical results omits it entirely.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Cortagen (Ala-Glu-Asp-Pro, AEDP) |
| cas | 335591-03-2 |
| formula | C17H26N4O9 |
| molar mass | 430.4 g/mol |
| purity | ≥ 98% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised powder is stored desiccated at -20 °C and protected from light. Once reconstituted, laboratory practice is refrigeration at 2-8 °C for short-term use, or aliquoting and freezing to avoid repeated freeze-thaw cycles. Handling information only; this compound has no approved human use. |
| solubility | Short hydrophilic peptide, readily soluble in sterile or bacteriostatic water and in dilute aqueous buffer. Lot-specific solubility is stated on the certificate of analysis. |
| sequence | Ala-Glu-Asp-Pro (AEDP) |
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crypto payment · research use only · not for human consumption
// others in Cognitive