Cardiogen
AEDR TETRAPEPTIDE · KHAVINSON BIOREGULATOR · 4 AA · IN VITRO ONLY
also: AEDR · Ala-Glu-Asp-Arg · H-Ala-Glu-Asp-Arg-OH
Cardiogen is a synthetic tetrapeptide (AEDR) from Khavinson's St Petersburg group, marketed as a cardiovascular 'bioregulator'. The primary published finding is a 2–5-fold rise in actin, tubulin, vimentin, lamin A and lamin C expression in cultured mouse embryonic fibroblasts, from which cardioprotection is inferred. No cardiac functional endpoint has been measured in any species, and no human study exists.
// our evidence grade — unedited
The cardiac claim rests on a single 2012 experiment in cultured mouse embryonic fibroblasts showing increased cytoskeletal and nuclear-matrix protein expression, plus later narrative reviews by the same authors; there is no animal cardiac outcome study, no human data, and no registered trial.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Cardiogen (Ala-Glu-Asp-Arg, AEDR) |
| purity | ≥ 98% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised powder is stored desiccated at -20 °C and protected from light. Once reconstituted, laboratory practice is refrigeration at 2-8 °C for short-term use, or aliquoting and freezing to avoid repeated freeze-thaw cycles. Handling information only; this compound has no approved human use. |
| solubility | Short hydrophilic peptide, readily soluble in sterile or bacteriostatic water and in dilute aqueous buffer. Lot-specific solubility is stated on the certificate of analysis. |
| sequence | Ala-Glu-Asp-Arg (AEDR) |
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crypto payment · research use only · not for human consumption
// others in Other