kisspeptin-10
KISS1R / GPR54 AGONIST DECAPEPTIDE
also: KP-10 · Kp-10 (human) · metastin 45-54
Kisspeptin-10 is the C-terminal decapeptide fragment of kisspeptin and a potent agonist at the KISS1R/GPR54 receptor, with real human intravenous infusion data showing stimulation of luteinising hormone and follicle-stimulating hormone. The widely circulated findings on sexual brain processing and penile tumescence were obtained with kisspeptin-54, not kisspeptin-10, and this distinction is routinely collapsed in marketing.
// our evidence grade — unedited
Kisspeptin-10 itself has genuine, well-conducted human pharmacology data on gonadotrophin secretion from the Dhillo group, but the sexual-desire and penile-tumescence findings it is marketed on were generated with kisspeptin-54, a different and longer peptide, and no approved indication exists for either.
We grade this compound and we sell it. The grade is set against our published criteria before any stocking decision and is not adjusted because it is in the catalogue.
read the full evidence →// specification
| full name | Kisspeptin-10 (human), metastin (45-54) |
| cas | 374675-21-5 |
| formula | C63H83N17O14 |
| molar mass | 1302.44 g/mol |
| purity | ≥ 99% HPLC |
| form | lyophilised powder, sealed vial |
| storage | Lyophilised peptide is typically stored desiccated at -20 C and protected from light; the RF-amide C-terminus and Trp residue make it sensitive to oxidation and light. Handling information only. |
| solubility | Water-soluble; the basic arginine residue and amidated C-terminus give good solubility in aqueous buffers, with sterile water or dilute aqueous buffer typically used in laboratory settings. |
| sequence | H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 (YNWNSFGLRF-NH2) |
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crypto payment · research use only · not for human consumption
// others in Sexual Health